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Department Goals and Objectives
To promote outstanding programs...
...of research and scholarship in neuroscience. Put simply, research is the engine that drives the department.
To provide outstanding instruction...
...and training in neuroscience to students at the undergraduate and graduate levels. Undergraduate students require a general education in science that will enable them to think logically and critically, and encourage them to seek understanding, regardless of their ultimate career goals. Graduate students require training that will enable them to become successful, independent scientific investigators.
Finally, as citizens of the University of Pittsburgh we accept the responsibility to provide service within the larger University community...
...and the still larger public community on matters that concern the function of the nervous system, including mental health and neurological diseases as well as more general matters of education in science.
Upcoming Seminars and Events
Department of Neuroscience Seminar:
February 13, 2012
Monday, 9:30 am
Travis E. Brown, Ph.D.
Department of Molecular Pharmacology, Physiology and Biotechnology
Brown University
Seminar Title: Interleukin-1 Beta Mediates LTP of Spinal Cord Glycinergic Synapses
Location: A219B Langley Hall
Sponsor: Kenneth P. Dietrich School of Arts and Sciences, Department of Neuroscience
Recent Faculty Publications
Card, JP, Kobiler O, Ludmir, EB, Desai, V, Sved AF, Enquist, LW., A Dual Infection Pseudorabies Virus Conditional
Reporter Approach to Identify Projections to
Collateralized Neurons in Complex Neural Circuits.,
PLoS One. 2011;6(6):e21141. Epub 2011 Jun 16.
Card JP, Kobiler O, McCambridge J, Ebdlahad S, Shan Z, Raizada MK, Sved AF, Enquist LW., Microdissection of neural networks by conditional reporter expression from a Brainbow herpesvirus., Proc Natl Acad Sci U S A. 2011 Feb 3. [Epub ahead of print], PMID: 21292985 [PubMed - as supplied by publisher]
Belujon P, Lodge DJ, Grace AA., Aberrant striatal plasticity is specifically associated with dyskinesia following levodopa treatment., Mov Disord. 2010 Aug 15;25(11):1568-76.PMID: 20623773 [PubMed - in process]
Bourassa EA, Fang X, Li X, Sved AF, Speth RC., AT(1) angiotensin II receptor and novel non-AT(1), non-AT(2) angiotensin II/III binding site in brainstem cardiovascular regulatory centers of the spontaneously hypertensive rat., Brain Res. 2010 Nov 4;1359:98-106. Epub 2010 Aug 31.PMID: 20807518 [PubMed - in process]
Card JP, Lois J, Sved AF., Distribution and phenotype of Phox2a-containing neurons in the adult sprague-dawley rat., J Comp Neurol. 2010 Jun 15;518(12):2202-20.PMID: 20437524 [PubMed - indexed for MEDLINE]
Cosgrove KE, Meriney SD, Barrionuevo G., High affinity group III mGluRs regulate mossy fiber input to CA3 interneurons., Hippocampus. 2010 Sep 7. [Epub ahead of print]PMID: 20824730 [PubMed - as supplied by publisher]
Curanović D, Lyman MG, Bou-Abboud C, Card JP, Enquist LW., Repair of the UL21 locus in pseudorabies virus Bartha enhances the kinetics of retrograde, transneuronal infection in vitro and in vivo., J Virol. 2009 Feb;83(3):1173-83. Epub 2008 Nov 19.PMID: 19019952 [PubMed - indexed for MEDLINE]
Dunn CA, Hall NJ, Colby CL., Spatial updating in monkey superior colliculus in the absence of the forebrain commissures: dissociation between superficial and intermediate layers., J Neurophysiol. 2010 Sep;104(3):1267-85. Epub 2010 Jul 7.PMID: 20610793 [PubMed - in process]
Dunn CA, Colby CL., Representation of the Ipsilateral Visual Field by Neurons in the Macaque Lateral Intraparietal Cortex Depends on the Forebrain Commissures., J Neurophysiol. 2010 Aug 18. [Epub ahead of print]PMID: 20660427 [PubMed - as supplied by publisher]
Eggan SM, Melchitzky DS, Sesack SR, Fish KN, Lewis DA., Relationship of cannabinoid CB1 receptor and cholecystokinin immunoreactivity in monkey dorsolateral prefrontal cortex., Neuroscience. 2010 Sep 15;169(4):1651-61. Epub 2010 Jun 11.PMID: 20542094 [PubMed - in process]
Ferrell RE, Baty CJ, Kimak MA, Karlsson JM, Lawrence EC, Franke-Snyder M, Meriney SD, Feingold E, Finegold DN., GJC2 missense mutations cause human lymphedema., Am J Hum Genet. 2010 Jun 11;86(6):943-8. Epub 2010 May 27.PMID: 20537300 [PubMed - indexed for MEDLINE]
Galván EJ, Cosgrove KE, Mauna JC, Card JP, Thiels E, Meriney SD, Barrionuevo G., Critical involvement of postsynaptic protein kinase activation in long-term potentiation at hippocampal mossy fiber synapses on CA3 interneurons., J Neurosci. 2010 Feb 24;30(8):2844-55.PMID: 20181582 [PubMed - indexed for MEDLINE]
Gielen M, Siegler Retchless B, Mony L, Johnson JW, Paoletti P., Mechanism of differential control of NMDA receptor activity by NR2 subunits, Nature. 2009 Jun 4;459(7247):703-7. Epub 2009 Apr 29.PMID: 19404260 [PubMed - indexed for MEDLINE]
Holmstrand EC, Asafu-Adjei J, Sampson AR, Blakely RD, Sesack SR., Ultrastructural localization of high-affinity choline transporter in the rat anteroventral thalamus and ventral tegmental area: differences in axon morphology and transporter distribution., J Comp Neurol. 2010 Jun 1;518(11):1908-24.PMID: 20394050 [PubMed - indexed for MEDLINE]
Koehnle TJ, Rinaman L., Early experience alters limbic forebrain Fos responses to a stressful interoceptive stimulus in young adult rats., Physiol Behav. 2010 May 11;100(2):105-15. Epub 2010 Feb 14.PMID: 20159026 [PubMed - indexed for MEDLINE]
Kotermanski SE, Wood JT, Johnson JW., Memantine binding to a superficial site on NMDA receptors contributes to partial trapping., J Physiol. 2009 Oct 1;587(Pt 19):4589-604. Epub 2009 Aug 17.PMID: 19687120 [PubMed - indexed for MEDLINE]
Lodge DJ, Grace AA., Developmental pathology, dopamine, stress and schizophrenia., Int J Dev Neurosci. 2010 Aug 19. [Epub ahead of print]PMID: 20727962 [PubMed - as supplied by publisher]
McCarron DA, Drüeke TB, Stricker EM., Science trumps politics: urinary sodium data challenge US dietary sodium guideline., Am J Clin Nutr. 2010 Oct 6. [Epub ahead of print] No abstract available. PMID: 20926523 [PubMed - as supplied by publisher
Moghaddam B., Dopamine in the thalamus: a hotbed for psychosis?, Biol Psychiatry. 2010 Jul 1;68(1):3-4. No abstract available. PMID: 20609835 [PubMed - in process]
Pehrson AL, Moghaddam B.; Impact of metabotropic glutamate 2/3 receptor stimulation on activated dopamine release and locomotion., Psychopharmacology (Berl). 2010 Sep;211(4):443-55. Epub 2010 Jun 29.PMID: 20585759 [PubMed - in process]
Rinaman L., Ascending projections from the caudal visceral nucleus of the solitary tract to brain regions involved in food intake and energy expenditure., Brain Res. 2010 Sep 2;1350:18-34. Epub 2010 Mar 27.PMID: 20353764 [PubMed - in process]
Stocker SD, Madden CJ, Sved AF., Excess dietary salt intake alters the excitability of central sympathetic networks., Physiol Behav. 2010 Jul 14;100(5):519-24. Epub 2010 May 1. Review.PMID: 20434471 [PubMed - indexed for MEDLINE]